This page keeps track of new/upcoming treatment options for chronic obstructive pulmonary disease (COPD). What’s in development? What’s promising? What’s available soon? Find out below… Current topics include MUC5AC inhibitors, gene therapy, P63+ progenitor cell transplantation, LABP-73 (NLR protein stimulant), Dupixent, IL-17, JadiCell, Zofin, and more.
Last updated: 2 years ago
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News
- Transplanting patients’ own lung cells offers hope of ‘cure’ for COPD Sep 11, 2023
- Is This Drug the Next COPD Breakthrough? Aug 7, 2023
- Dupixent® (Dupilumab) Demonstrates Potential to Become First Biologic to Treat COPD Mar 23, 2023
- Therapeutic Solutions International Advances Chronic Obstructive Pulmonary Disease Program Mar 13, 2023
- Synairgen announces positive data from interim analysis of SNG001 trial in COPD patients Sep 8, 2020
- Drug development for severe respiratory diseases supported with $3.9 million grant: New drug candidate targets asthma, COPD, other progressive lung diseases Aug 12, 2020
- AstraZeneca Wins FDA Approval for COPD Treatment Jul 24, 2020
- Verona Pharma Raises $200 Million to support Phase 3 ENHANCE clinical program in COPD Jul 17, 2020
- Twice-daily Budesonide/Glycopyrrolate/Formoterol Significantly Lowered Exacerbations in Patients with Moderate or Severe COPD Jun 24, 2020
- Lung Denervation System Named FDA Breakthrough Device Jun 16, 2020
- Nuvaira Announces FDA Breakthrough Designation for AIRFLOW-3 Pivotal Trial Device Jun 8, 2020
- A New Report Confirms Significant Benefits in Patient Reported Outcomes at One Year Following the Non-Surgical Zephyr Valve Procedure for COPD/Emphysema May 12, 2020
- Lung Volume Reduction Coil Treatment Enables Recovery in Severe COPD Cases Mar 11, 2020
- Inhalation therapy shows promise against pulmonary fibrosis in mice, rats Feb 28, 2020
- Verona Pharma announces publication of Phase 2b clinical trial results for ensifentrine, a maintenance treatment for chronic obstructive pulmonary disease (COPD) Feb 14, 2020
- New hope for COPD patients possible with in-home device Feb 4, 2020
- Verona Pharma Reports Positive Top-line Data in Phase 2b COPD Study with Nebulized Ensifentrine on Top of Tiotropium Therapy Jan 13, 2020
- Cancer drugs could potentially treat COPD Jan 6, 2020
- Antiarrhythmic drug could also treat PAH, COPD Dec 16, 2019
- There’s now a life-changing treatment (Zephyr valve system) for COPD patients in Georgia Dec 15, 2019
- New Research Gives Hope for Slowing Progression and Mortality of Chronic Obstructive Pulmonary Disease (COPD) Nov 13, 2019
- COPD Foundation: COPD Awareness Month is Here! Nov 1, 2019
- Oscillating Vest Keeps COPD Patients Out of Hospital: Exacerbations reduced with technology initially designed for use in CF Oct 23, 2019
- Temple AIRFLOW-3 trial offers new approach to treating COPD Oct 22, 2019
- Verona Pharma Completes Enrollment in Phase 2b Clinical Trial for Ensifentrine in moderate-to-severe COPD Oct 17, 2019
- Bayer Will Invest $30M in Joint Research Lab for COPD, Other Chronic Lung Diseases Oct 15, 2019
- Verona Pharma to Present Phase 2 Symptom Data with Ensifentrine (RPL554) in COPD at CHEST 2019 Oct 15, 2019
- AzurRx BioPharma Announces Positive Results from Phase 2 Trial with MS1819 in Cystic Fibrosis Patients Sep 25, 2019
- AstraZeneca to present next wave of science in respiratory disease at ERS International Congress Sep 25, 2019
- PT010 Phase III ETHOS Trial Met Its Primary Endpoint in COPD Aug 29, 2019
- Circassia Pharma Receives 2nd FDA Approval for COPD Treatment in 2 Weeks Apr 18, 2019
- Circassia Announces FDA Approval of Duaklir for Maintenance Treatment of Chronic Obstructive Pulmonary Disease Apr 1, 2019
- AI-powered digital treatment can aid COPD treatment: Study Mar 9, 2019
- Queen’s Researchers make breakthrough in chronic lung disease Mar 7, 2019
- Verona announces positive results from Phase II COPD trial Mar 5, 2019
- WebMD: Daily Aspirin Might Ease COPD Flare-Ups Mar 4, 2019
- Nuvaira Raises $79M for COPD Treatment Device Feb 11, 2019
- New COPD treatment at UofL Hospital is a ‘landmark development’ Feb 6, 2019
- Researchers breathe new life into COPD research using mouse models Jan 31, 2019
- FDA Approves Generic Inhalation Treatment for Asthma, COPD Jan 30, 2019
- FDA approves first generic Advair Diskus Jan 30, 2019
- Inhalable MRNA: New Delivery Method Could Help Treat Patients Of Lung Disease Jan 11, 2019
- New Shock Treatment Showing Promise For COPD Patients Jan 7, 2019
- Engineers create an inhalable form of messenger RNA Jan 4, 2019
- Teva’s ProAir Digihaler FDA Approved to Monitor Asthma and COPD Treatment Dec 26, 2018
- Synairgen Developing COPD Treatment To Hold Off Further Viral Damage Dec 18, 2018
- Zapping airway nerves may help COPD patients breathe Nov 29, 2018
- FDA Approves Revefenacin, a Once-a-Day Nebulized LAMA, for COPD Nov 9, 2018
- Theravance Biopharma and Mylan Receive FDA Approval for YUPELRI™ (revefenacin) in Adults with Chronic Obstructive Pulmonary Disease Nov 9, 2018
- Zapping Airway Nerves May Help COPD Patients Sep 18, 2018
- Testosterone replacement therapy could slow the progression of COPD Sep 18, 2018
- FDA-Approved Valve Treatment For COPD Seeing Positive Results Jul 24, 2018
- FDA approves novel device for treating breathing difficulty from severe emphysema Jun 29, 2018
Research
- Harnessing the Therapeutic Potential of Stem Cells in the Management of Chronic Obstructive Pulmonary Disease Aug 31, 2023
- Dupilumab for COPD with Type 2 Inflammation Indicated by Eosinophil Counts Jul 20, 2023
- Unleashing the Power of IL-17: A Promising Frontier in Chronic Obstructive Pulmonary Disease (COPD) Treatment Jul 16, 2023
- Navafenterol (AZD8871) in patients with COPD: a randomized, double-blind, phase I study evaluating safety and pharmacodynamics of single doses of this novel, inhaled, long-acting, dual-pharmacology bronchodilator Sep 9, 2020
- Therapeutic effects of black seed oil supplementation on chronic obstructive pulmonary disease patients: A randomized controlled double blind clinical trial Aug 13, 2020
- Biomarkers in Chronic Obstructive Pulmonary Disease: The Gateway to Precision Medicine Aug 12, 2020
- The Potential Role and Regulatory Mechanisms of MUC5AC in Chronic Obstructive Pulmonary Disease Aug 11, 2020
- Impaired lnc-IL7R modulatory mechanism of Toll-like receptors is associated with an exacerbator phenotype of chronic obstructive pulmonary disease. Aug 11, 2020
- Preventive and therapeutic effectiveness of Sanfu acupoint herbal patching for chronic obstructive pulmonary disease at stable stages: a systematic review and meta-analysis Aug 4, 2020
- Platelets in chronic obstructive pulmonary disease: An update on pathophysiology and implications for antiplatelet therapy Jul 29, 2020
- Therapeutic Effects of SRT2104 on Lung Injury in Rats with Emphysema via Reduction of Type II Alveolar Epithelial Cell Senescence Jul 28, 2020
- Difference in the metabolic characteristics of chronic obstructive pulmonary disease patients and healthy adults Jul 24, 2020
- ADAM15 deficiency increased pulmonary inflammation in mice and is strongly linked to the pathogenesis of COPD Jul 20, 2020
- Fecal microbial transplantation (FMT) and a high fiber diet (HFD) attenuates emphysema development by suppressing inflammation and apoptosis Jul 17, 2020
- ADAM15 expression is increased in lung CD8+ T cells, macrophages, and bronchial epithelial cells in patients with COPD and is inversely related to airflow obstruction Jul 16, 2020
- Mediated Drug Release from Nano-Vehicles by Black Phosphorus Quantum Dots for Efficient Therapy of Chronic Obstructive Pulmonary Disease Jul 15, 2020
- Vitamin B12 Supplementation and NT-proBNP Levels in COPD Patients: A Secondary Analysis of a Randomized and Controlled Study Jul 14, 2020
- PR1P as a novel therapeutic agent for the treatment of emphysema or other lung diseases characterized by VEGF signaling dysregulation Jul 14, 2020
- Triple Inhaled Therapy at Two Glucocorticoid Doses in Moderate-to-Very-Severe COPD Jul 2, 2020
- Long non-coding RNA NNT-AS1 regulates proliferation, apoptosis, inflammation and airway remodeling of chronic obstructive pulmonary disease via targeting miR-582-5p/FBXO11 axis Jul 2, 2020
- The Role of Toll-Like Receptors 2 (TLR2) and 4 (TLR4) in the Pathogenesis of Chronic Obstructive Pulmonary Disease Jun 23, 2020
- The Adjunctive Effect of Intravenous Magnesium Sulfate in Acute Exacerbation of COPD Jun 15, 2020
- CXCR2 antagonist for patients with chronic obstructive pulmonary disease with chronic mucus hypersecretion: a phase 2b trial Jun 12, 2020
- NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD Jun 8, 2020
- Effects of compound Caoshi silkworm granules (CCSGs) on stable COPD patients and their relationship with gut microbiota May 29, 2020
- The Relevance of Targeting Treatment to Small Airways in Asthma and COPD: the newest technological therapeutic advances Mar 24, 2020
- Hesperidin alleviated inflammation and oxidative stress responses in COPD mice, associated with SIRT1/PGC-1α/NF-κB signaling axis: a new direction for COPD treatment Mar 13, 2020
- The Efficacy of Lung Volume Reduction Coil Treatment in Patients with Severe Chronic Obstructive Pulmonary Disease (COPD) Type II Respiratory Failure Mar 3, 2020
- The key role of macrophage depolarization in the treatment of COPD with ergosterol Dec 20, 2019
- Bu-Shen-Fang-Chuan formula (BSFCF) attenuates T-lymphocytes recruitment and improves pulmonary function in rat model of COPD through suppressing CXCL9/CXCL10/CXCL11-CXCR3 axis Dec 17, 2019
- Oral formulation angiotensin-(1-7) therapy attenuates pulmonary and systemics damage in mice with emphysema Dec 4, 2019
- Dynamic changes of gut and lung microorganisms during chronic obstructive pulmonary disease exacerbations: possibly a target for future therapeutics Nov 29, 2019
- Effectiveness of Xin Jia Xuan Bai Cheng Qi Decoction in treating acute exacerbation of chronic obstructive pulmonary disease: study protocol Nov 28, 2019
- Dual Role For A MEK Inhibitor As A Modulator Of Inflammation And Host Defense Mechanisms With Potential Therapeutic Application In COPD Nov 26, 2019
- Role of melatonin as an SIRT1 enhancer in chronic obstructive pulmonary disease induced by cigarette smoke Nov 25, 2019
- LABAs and p38MAPK Inhibitors Reverse the Corticosteroid-Insensitivity of IL-8 in Airway Smooth Muscle Cells of COPD Nov 22, 2019
- Chronic obstructive pulmonary disease and phenotypes: a state-of-the-art [Review] Nov 15, 2019
- Acumapimod (BCT197) to Treat Acute Exacerbations of COPD Nov 4, 2019
- Inhibitors of ErbB kinases have therapeutic potential in neutrophilic inflammatory diseases, including chronic obstructive pulmonary disease (COPD) Oct 15, 2019
- Airway pharmacology: treatment options and algorithms to treat patients with chronic obstructive pulmonary disease Oct 11, 2019
- Inhalable nanotherapeutics to improve treatment efficacy for common lung diseases Oct 10, 2019
- Lipids in COPD: A Target for Future Therapy? [PDF] Oct 2, 2019
- Allyl isothiocyanate (AITC) may reverse the expression of MRP1 in COPD rats via the Notch1 signaling pathway Sep 30, 2019
- Therapeutic efficacy of the aqueous extract of the stem bark of Ximenia americana L. in the treatment of experimental COPD in rats Sep 29, 2019
- DT-0111: a novel drug-candidate for the treatment of COPD and chronic cough Sep 27, 2019
- COPD: preclinical models and emerging therapeutic targets Sep 20, 2019
- Dissection of Pharmacological Mechanism of Chinese Herbal Medicine Yihuo Huatan Formula on Chronic Obstructive Pulmonary Disease Sep 17, 2019
- Carbocisteine inhibits the expression of Muc5b in COPD mouse model Sep 16, 2019
- Anti-viral immunity is impaired in COPD patients with frequent exacerbations Sep 12, 2019
- Curcumin ameliorates chronic obstructive pulmonary disease by modulating autophagy and endoplasmic reticulum stress through regulation of SIRT1 in a rat model Sep 12, 2019
- miRNA‑101‑3p.1 facilitates COPD progression by activating the EGFR/PI3K/AKT signaling pathway Sep 9, 2019
- Therapeutic potential of BLT1 antagonist for COPD: involvement of inducing autophagy and ameliorating inflammation Sep 4, 2019
- Immune-Modulation in Chronic Obstructive Pulmonary Disease: Current Concepts and Future Strategies Sep 3, 2019
- Ensifentrine (RPL554): an investigational PDE3/4 inhibitor for the treatment of COPD Sep 1, 2019
- Pharmacological treatment and current controversies in COPD Aug 29, 2019
- Efficacy and safety of inhaled alpha-1-antitrypsin in severe COPD patients with alpha-1-antitrypsin deficiency Aug 29, 2019
- CARM1 contributes to airway repair and regeneration by regulating airway epithelial cell senescence Aug 28, 2019
- Wharton’s jelly-derived mesenchymal stem cells show pulmonary regenerative effects in COPD mouse model Aug 24, 2019
- Mepolizumab in the treatment of eosinophilic chronic obstructive pulmonary disease Aug 7, 2019
- Personalized medicine for patients with COPD: where are we? Jul 9, 2019
- Ergosterol attenuates cigarette smoke extract-induced COPD by modulating inflammation, oxidative stress and apoptosis in vitro and in vivo Jul 3, 2019
- Chemokines in COPD: From Implication to Therapeutic Use Jun 6, 2019
- 12-month randomised controlled trial of ginseng extract for moderate COPD: no significant differences between ginseng and placebo May 15, 2019
- MicroRNAs in COPD: small molecules with big potential Apr 25, 2019
- Macrolides for treatment of chronic obstructive pulmonary disease Apr 3, 2019
- Vitamin D reduces the serum levels of inflammatory cytokines in rat models of chronic obstructive pulmonary disease – “findings suggest that vitamin D supplementation could be a new clinical approach for the treatment of COPD” Mar 29, 2019
- Genetic Advances in Chronic Obstructive Pulmonary Disease: Insights from COPDGene Mar 20, 2019
- Can treating vitamin D deficiency reduce exacerbations of chronic obstructive pulmonary disease? Mar 18, 2019
- Effect of long-term corticosteroid treatment on microRNA and gene-expression profiles in Chronic Obstructive Pulmonary Disease Mar 7, 2019
- Once daily long-acting beta2-agonists and long-acting muscarinic antagonists in a combined inhaler versus placebo for chronic obstructive pulmonary disease Mar 6, 2019
- Endothelial Progenitor Cells as Pathogenetic and Diagnostic Factors, and Potential Targets for GLP-1 in Combination with Metabolic Syndrome and Chronic Obstructive Pulmonary Disease Mar 4, 2019
- Inflammatory endotypes in COPD Mar 4, 2019
- Extrafine triple therapy delays COPD clinically important deterioration vs ICS/LABA, LAMA, or LABA/LAMA Feb 28, 2019
- PI3K/Akt-Nrf2 and Anti-Inflammation Effect of Macrolides in Chronic Obstructive Pulmonary Disease Feb 27, 2019
- Correlation between hypocalcemia and acute exacerbation of chronic obstructive pulmonary disease Feb 26, 2019
- Pathobiological mechanisms underlying metabolic syndrome (MetS) in chronic obstructive pulmonary disease (COPD): clinical significance and therapeutic strategies Feb 26, 2019
- Efficacy and safety of Xuebijing injection and its influence on immunomodulation in acute exacerbations of chronic obstructive pulmonary disease: study protocol Feb 18, 2019
- Protective effect of amygdalin on epithelial-mesenchymal transformation in experimental chronic obstructive pulmonary disease mice Jan 30, 2019
- Deducting MicroRNA-Mediated Changes Common in Bronchial Epithelial Cells of Asthma and Chronic Obstructive Pulmonary Disease-A Next-Generation Sequencing-Guided Bioinformatic Approach Jan 28, 2019
- Notch promotes DNMT-mediated hypermethylation of Klotho leads to COPD-related inflammation Jan 26, 2019
- Evaluation of plasma antimicrobial peptide LL-37 and nuclear factor-kappaB levels in stable chronic obstructive pulmonary disease Jan 25, 2019
- Targeted Treatments for Chronic Obstructive Pulmonary Disease (COPD) Using Low-Molecular-Weight Drugs (LMWDs) Jan 25, 2019
- Introduction to Precision Medicine in COPD Jan 24, 2019
- Louqin Zhisou Decoction Inhibits Mucus Hypersecretion for Acute Exacerbation of Chronic Obstructive Pulmonary Disease Rats by Suppressing EGFR-PI3K-AKT Signaling Pathway and Restoring Th17/Treg Balance Jan 20, 2019
- Protective effects of astragaloside IV on IL-8-treated diaphragmatic muscle cells Jan 17, 2019
- Loss of the adhesion G-protein coupled receptor ADGRF5 in mice induces airway inflammation and the expression of CCL2 in lung endothelial cells Jan 17, 2019
- The COPD Pipeline 40 Jan 14, 2019
- Neuromuscular electrical stimulation improves muscle atrophy induced by chronic hypoxia-hypercapnia through the MicroRNA-486/PTEN/FoxO1 pathway Jan 14, 2019
- Effect of Indacaterol/Glycopyrronium on Pulmonary Perfusion and Ventilation in Hyperinflated COPD Patients (CLAIM): A Double-Blind, Randomised, Crossover Trial Jan 14, 2019
- Subcutaneous administration of neutralizing antibodies to endothelial monocyte-activating protein II attenuates cigarette smoke-induced lung injury in mice Jan 10, 2019
- Roles of TRPA1 and TRPV1 in Cigarette Smoke -induced Airway Epithelial Cell Injury Model Jan 9, 2019
- miR-145-5p is associated with smoke-related chronic obstructive pulmonary disease via targeting KLF5 Jan 9, 2019
- Mitochondrial regulation of airway smooth muscle functions in health and pulmonary diseases Jan 8, 2019
- DNA repair as an emerging target for COPD-lung cancer overlap Jan 7, 2019
- Effects of Scutellaria baicalensis Extract on Cigarette Smoke-Induced Airway Inflammation in a Murine Model of Chronic Obstructive Pulmonary Disease Jan 7, 2019
- Polymeric Nanoparticles for the Delivery of miRNA to Treat Chronic Obstructive Pulmonary Disease (COPD) Jan 4, 2019
- A retinoid X receptor partial agonist attenuates pulmonary emphysema and airway inflammation Jan 3, 2019
- Updated guidelines for chronic obstructive pulmonary disease. Dec 29, 2018
- Electroacupuncture Improves Pulmonary Function of Rats with Chronic Obstructive Pulmonary Disease by Down-regulating Inflammatory Reaction and Expression of Macrophage Migration Inhibitory Factor/CD 74-CD 44/p 38 MAPK Signaling in Lung Tissues Dec 25, 2018
- Naringenin attenuates inflammation in chronic obstructive pulmonary disease in cigarette smoke induced mouse model and involves suppression of NF-κB Dec 24, 2018
- Possible role of airway microvascular permeability on airway obstruction in patients with chronic obstructive pulmonary disease Dec 21, 2018
- Advancing COPD Therapy: Opportunities, Challenges and Excitement Dec 18, 2018
- Multi-target natural products as alternatives against oxidative stress in Chronic Obstructive Pulmonary Disease (COPD) Dec 11, 2018
Clinical Trials
- Dose-range Finding Efficacy and Safety Study for QBW251 in COPD Patients Jul 29, 2020
- Fiber Metabolism in Chronic Obstructive Pulmonary Disease Jul 7, 2020
- Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab (SAR231893) in Patients With Moderate to Severe COPD With Type 2 Inflammation Jul 2, 2020
- A Study of RPL554 Drug Administered by Metered Dose Inhaler to Treat Chronic Obstructive Pulmonary Disease Feb 24, 2020
- The Safety and Feasibility of UMC119-06 Cell Therapy (Mesenchymal Stem Cells) in Subjects With Chronic Obstructive Pulmonary Disease Dec 20, 2019
- Mesenchymal Stem Cells in the Treatment of Subjects With Advance Chronic Obstructive Pulmonary Disease (COPD) Dec 12, 2019
- The Use of Benralizumab, an Interleukin-5 Receptor-α Monoclonal Antibody as Treatment of Acute Exacerbations of Airways Disease Sep 23, 2019
- Study to evaluate the impact of inhaled PT003 in moderate to severe COPD patients Sep 12, 2019
- Investigate the Safety, Tolerability and Pharmacokinetics of CHF6523 in Healthy and in COPD Subjects Aug 1, 2019
- Photobiomodulation in Individuals With Chronic Obstructive Pulmonary Disease Jul 8, 2019
- The Effectiveness of Bottle-PEP in Chronic Obstructive Pulmonary Disease Apr 2, 2019
- The Effect of FP-025, a MMP-12 Inhibitor, on Airway Responses and Airway Inflammation Mar 1, 2019
- The Effects of RPL554 in Addition to Tiotropium in COPD Patients [Completed] Feb 27, 2019
- Arbidol for COPD Exacerbations Feb 22, 2019
- A Proof-of-mechanism Study of Multiple, Oral Doses of Fevipiprant (QAW039) in COPD Patients With Eosinophilia Jan 18, 2019
- Safety and Tolerability of MEDI3506 in Healthy Subjects, in Subjects With COPD and Healthy Japanese Subjects Jan 8, 2019
- Efficacy Study of Nebulized TD-4208 for Chronic Obstructive Pulmonary Disease (COPD) Dec 31, 2018
- A 52-Week Parallel Group Safety Study of TD-4208 in Chronic Obstructive Pulmonary Disease (COPD) Dec 31, 2018
- A Study to Test a Potential New Treatment for COPD Patients Suffering From the Common Cold or Influenza Dec 31, 2018
- Effect of Vitamin D3 on Lung Function and Exercise Tolerance in COPD Patients Dec 25, 2018
- Alvelestat (MPH996) for the Treatment of ALpha-1 ANTitrypsin Deficiency Dec 18, 2018
- A Single Inhalation Dose Study to Assess Efficacy, Pharmacokinetics (PK), Safety and Tolerability of AZD8871 in Patients With Long-term Lung Diseases Dec 8, 2018
- A 12-week Study Treating Participants Who Have alpha1-antitrypsin-related COPD With Alvelestat (MPH966) or Placebo Nov 15, 2018
- Prevention of Acute Exacerbation in Subjects With COPD by Bacterial Decolonization in Lower Respiratory Tract Nov 15, 2018
- Home Non Invasive Ventilation (NIV) Treatment for COPD-patients After a NIV-treated Exacerbation Nov 14, 2018
- Use of Autologous, Adult Adipose-Derived Stem/Stromal Cells In Chronic Lung Disorders Nov 8, 2018
- A Study to Assess the Efficacy of a 5-day, 10- mg PBF-680 Oral Administration on Late Asthmatic Responses (LAR) in Mild to Moderate Asthmatic Patients Nov 6, 2018
- Autologous Transplantation of Bronchial Basal Cells for Treatment of COPD Nov 4, 2018
- Anti-ST2 (MSTT1041A) in COPD (COPD-ST2OP) Oct 31, 2018
- A Pilot Study of the Use of Metformin to Reduce Airway Glucose in COPD Aug 29, 2018
Projects
- Transplanting patients’ own lung cells offers hope of ‘cure’ for COPD Sep 11, 2023
- Harnessing the Therapeutic Potential of Stem Cells in the Management of Chronic Obstructive Pulmonary Disease Aug 31, 2023
- Is This Drug the Next COPD Breakthrough? Aug 7, 2023
- Dupilumab for COPD with Type 2 Inflammation Indicated by Eosinophil Counts Jul 20, 2023
- Unleashing the Power of IL-17: A Promising Frontier in Chronic Obstructive Pulmonary Disease (COPD) Treatment Jul 16, 2023
- Zofin to Treat Chronic Obstructive Pulmonary Disease (COPD) Mar 23, 2023
- Dupixent® (Dupilumab) Demonstrates Potential to Become First Biologic to Treat COPD Mar 23, 2023
- Therapeutic Solutions International Advances Chronic Obstructive Pulmonary Disease Program Mar 13, 2023
- Navafenterol (AZD8871) in patients with COPD: a randomized, double-blind, phase I study evaluating safety and pharmacodynamics of single doses of this novel, inhaled, long-acting, dual-pharmacology bronchodilator Sep 9, 2020
- Synairgen announces positive data from interim analysis of SNG001 trial in COPD patients Sep 8, 2020
- Therapeutic effects of black seed oil supplementation on chronic obstructive pulmonary disease patients: A randomized controlled double blind clinical trial Aug 13, 2020
- Drug development for severe respiratory diseases supported with $3.9 million grant: New drug candidate targets asthma, COPD, other progressive lung diseases Aug 12, 2020
- Biomarkers in Chronic Obstructive Pulmonary Disease: The Gateway to Precision Medicine Aug 12, 2020
- The Potential Role and Regulatory Mechanisms of MUC5AC in Chronic Obstructive Pulmonary Disease Aug 11, 2020
- Impaired lnc-IL7R modulatory mechanism of Toll-like receptors is associated with an exacerbator phenotype of chronic obstructive pulmonary disease. Aug 11, 2020
- Preventive and therapeutic effectiveness of Sanfu acupoint herbal patching for chronic obstructive pulmonary disease at stable stages: a systematic review and meta-analysis Aug 4, 2020
- Platelets in chronic obstructive pulmonary disease: An update on pathophysiology and implications for antiplatelet therapy Jul 29, 2020
- Dose-range Finding Efficacy and Safety Study for QBW251 in COPD Patients Jul 29, 2020
- Therapeutic Effects of SRT2104 on Lung Injury in Rats with Emphysema via Reduction of Type II Alveolar Epithelial Cell Senescence Jul 28, 2020
- AstraZeneca Wins FDA Approval for COPD Treatment Jul 24, 2020
- Difference in the metabolic characteristics of chronic obstructive pulmonary disease patients and healthy adults Jul 24, 2020
- ADAM15 deficiency increased pulmonary inflammation in mice and is strongly linked to the pathogenesis of COPD Jul 20, 2020
- Fecal microbial transplantation (FMT) and a high fiber diet (HFD) attenuates emphysema development by suppressing inflammation and apoptosis Jul 17, 2020
- Verona Pharma Raises $200 Million to support Phase 3 ENHANCE clinical program in COPD Jul 17, 2020
- ADAM15 expression is increased in lung CD8+ T cells, macrophages, and bronchial epithelial cells in patients with COPD and is inversely related to airflow obstruction Jul 16, 2020
- Mediated Drug Release from Nano-Vehicles by Black Phosphorus Quantum Dots for Efficient Therapy of Chronic Obstructive Pulmonary Disease Jul 15, 2020
- Vitamin B12 Supplementation and NT-proBNP Levels in COPD Patients: A Secondary Analysis of a Randomized and Controlled Study Jul 14, 2020
- PR1P as a novel therapeutic agent for the treatment of emphysema or other lung diseases characterized by VEGF signaling dysregulation Jul 14, 2020
- Fiber Metabolism in Chronic Obstructive Pulmonary Disease Jul 7, 2020
- Triple Inhaled Therapy at Two Glucocorticoid Doses in Moderate-to-Very-Severe COPD Jul 2, 2020
- Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab (SAR231893) in Patients With Moderate to Severe COPD With Type 2 Inflammation Jul 2, 2020
- Long non-coding RNA NNT-AS1 regulates proliferation, apoptosis, inflammation and airway remodeling of chronic obstructive pulmonary disease via targeting miR-582-5p/FBXO11 axis Jul 2, 2020
- Twice-daily Budesonide/Glycopyrrolate/Formoterol Significantly Lowered Exacerbations in Patients with Moderate or Severe COPD Jun 24, 2020
- The Role of Toll-Like Receptors 2 (TLR2) and 4 (TLR4) in the Pathogenesis of Chronic Obstructive Pulmonary Disease Jun 23, 2020
- Lung Denervation System Named FDA Breakthrough Device Jun 16, 2020
- The Adjunctive Effect of Intravenous Magnesium Sulfate in Acute Exacerbation of COPD Jun 15, 2020
- CXCR2 antagonist for patients with chronic obstructive pulmonary disease with chronic mucus hypersecretion: a phase 2b trial Jun 12, 2020
- NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD Jun 8, 2020
- Nuvaira Announces FDA Breakthrough Designation for AIRFLOW-3 Pivotal Trial Device Jun 8, 2020
- Effects of compound Caoshi silkworm granules (CCSGs) on stable COPD patients and their relationship with gut microbiota May 29, 2020
- A New Report Confirms Significant Benefits in Patient Reported Outcomes at One Year Following the Non-Surgical Zephyr Valve Procedure for COPD/Emphysema May 12, 2020
- The Relevance of Targeting Treatment to Small Airways in Asthma and COPD: the newest technological therapeutic advances Mar 24, 2020
- Hesperidin alleviated inflammation and oxidative stress responses in COPD mice, associated with SIRT1/PGC-1α/NF-κB signaling axis: a new direction for COPD treatment Mar 13, 2020
- Lung Volume Reduction Coil Treatment Enables Recovery in Severe COPD Cases Mar 11, 2020
- The Efficacy of Lung Volume Reduction Coil Treatment in Patients with Severe Chronic Obstructive Pulmonary Disease (COPD) Type II Respiratory Failure Mar 3, 2020
- Inhalation therapy shows promise against pulmonary fibrosis in mice, rats Feb 28, 2020
- A Study of RPL554 Drug Administered by Metered Dose Inhaler to Treat Chronic Obstructive Pulmonary Disease Feb 24, 2020
- Verona Pharma announces publication of Phase 2b clinical trial results for ensifentrine, a maintenance treatment for chronic obstructive pulmonary disease (COPD) Feb 14, 2020
- New hope for COPD patients possible with in-home device Feb 4, 2020
- Verona Pharma Reports Positive Top-line Data in Phase 2b COPD Study with Nebulized Ensifentrine on Top of Tiotropium Therapy Jan 13, 2020
- Cancer drugs could potentially treat COPD Jan 6, 2020
- The Safety and Feasibility of UMC119-06 Cell Therapy (Mesenchymal Stem Cells) in Subjects With Chronic Obstructive Pulmonary Disease Dec 20, 2019
- The key role of macrophage depolarization in the treatment of COPD with ergosterol Dec 20, 2019
- Bu-Shen-Fang-Chuan formula (BSFCF) attenuates T-lymphocytes recruitment and improves pulmonary function in rat model of COPD through suppressing CXCL9/CXCL10/CXCL11-CXCR3 axis Dec 17, 2019
- Antiarrhythmic drug could also treat PAH, COPD Dec 16, 2019
- There’s now a life-changing treatment (Zephyr valve system) for COPD patients in Georgia Dec 15, 2019
- Mesenchymal Stem Cells in the Treatment of Subjects With Advance Chronic Obstructive Pulmonary Disease (COPD) Dec 12, 2019
- Oral formulation angiotensin-(1-7) therapy attenuates pulmonary and systemics damage in mice with emphysema Dec 4, 2019
- Dynamic changes of gut and lung microorganisms during chronic obstructive pulmonary disease exacerbations: possibly a target for future therapeutics Nov 29, 2019
- Effectiveness of Xin Jia Xuan Bai Cheng Qi Decoction in treating acute exacerbation of chronic obstructive pulmonary disease: study protocol Nov 28, 2019
- Dual Role For A MEK Inhibitor As A Modulator Of Inflammation And Host Defense Mechanisms With Potential Therapeutic Application In COPD Nov 26, 2019
- Role of melatonin as an SIRT1 enhancer in chronic obstructive pulmonary disease induced by cigarette smoke Nov 25, 2019
- LABAs and p38MAPK Inhibitors Reverse the Corticosteroid-Insensitivity of IL-8 in Airway Smooth Muscle Cells of COPD Nov 22, 2019
- Chronic obstructive pulmonary disease and phenotypes: a state-of-the-art [Review] Nov 15, 2019
- New Research Gives Hope for Slowing Progression and Mortality of Chronic Obstructive Pulmonary Disease (COPD) Nov 13, 2019
- Acumapimod (BCT197) to Treat Acute Exacerbations of COPD Nov 4, 2019
- COPD Foundation: COPD Awareness Month is Here! Nov 1, 2019
- Oscillating Vest Keeps COPD Patients Out of Hospital: Exacerbations reduced with technology initially designed for use in CF Oct 23, 2019
- Temple AIRFLOW-3 trial offers new approach to treating COPD Oct 22, 2019
- Verona Pharma Completes Enrollment in Phase 2b Clinical Trial for Ensifentrine in moderate-to-severe COPD Oct 17, 2019
- Bayer Will Invest $30M in Joint Research Lab for COPD, Other Chronic Lung Diseases Oct 15, 2019
- Inhibitors of ErbB kinases have therapeutic potential in neutrophilic inflammatory diseases, including chronic obstructive pulmonary disease (COPD) Oct 15, 2019
- Verona Pharma to Present Phase 2 Symptom Data with Ensifentrine (RPL554) in COPD at CHEST 2019 Oct 15, 2019
- Airway pharmacology: treatment options and algorithms to treat patients with chronic obstructive pulmonary disease Oct 11, 2019
- Inhalable nanotherapeutics to improve treatment efficacy for common lung diseases Oct 10, 2019
- Lipids in COPD: A Target for Future Therapy? [PDF] Oct 2, 2019
- Allyl isothiocyanate (AITC) may reverse the expression of MRP1 in COPD rats via the Notch1 signaling pathway Sep 30, 2019
- Therapeutic efficacy of the aqueous extract of the stem bark of Ximenia americana L. in the treatment of experimental COPD in rats Sep 29, 2019
- DT-0111: a novel drug-candidate for the treatment of COPD and chronic cough Sep 27, 2019
- AzurRx BioPharma Announces Positive Results from Phase 2 Trial with MS1819 in Cystic Fibrosis Patients Sep 25, 2019
- AstraZeneca to present next wave of science in respiratory disease at ERS International Congress Sep 25, 2019
- The Use of Benralizumab, an Interleukin-5 Receptor-α Monoclonal Antibody as Treatment of Acute Exacerbations of Airways Disease Sep 23, 2019
- COPD: preclinical models and emerging therapeutic targets Sep 20, 2019
- Dissection of Pharmacological Mechanism of Chinese Herbal Medicine Yihuo Huatan Formula on Chronic Obstructive Pulmonary Disease Sep 17, 2019
- Carbocisteine inhibits the expression of Muc5b in COPD mouse model Sep 16, 2019
- Anti-viral immunity is impaired in COPD patients with frequent exacerbations Sep 12, 2019
- Curcumin ameliorates chronic obstructive pulmonary disease by modulating autophagy and endoplasmic reticulum stress through regulation of SIRT1 in a rat model Sep 12, 2019
- Study to evaluate the impact of inhaled PT003 in moderate to severe COPD patients Sep 12, 2019
- miRNA‑101‑3p.1 facilitates COPD progression by activating the EGFR/PI3K/AKT signaling pathway Sep 9, 2019
- Therapeutic potential of BLT1 antagonist for COPD: involvement of inducing autophagy and ameliorating inflammation Sep 4, 2019
- Immune-Modulation in Chronic Obstructive Pulmonary Disease: Current Concepts and Future Strategies Sep 3, 2019
- Ensifentrine (RPL554): an investigational PDE3/4 inhibitor for the treatment of COPD Sep 1, 2019
- Pharmacological treatment and current controversies in COPD Aug 29, 2019
- Efficacy and safety of inhaled alpha-1-antitrypsin in severe COPD patients with alpha-1-antitrypsin deficiency Aug 29, 2019
- PT010 Phase III ETHOS Trial Met Its Primary Endpoint in COPD Aug 29, 2019
- CARM1 contributes to airway repair and regeneration by regulating airway epithelial cell senescence Aug 28, 2019
- Wharton’s jelly-derived mesenchymal stem cells show pulmonary regenerative effects in COPD mouse model Aug 24, 2019
- Mepolizumab in the treatment of eosinophilic chronic obstructive pulmonary disease Aug 7, 2019
- Investigate the Safety, Tolerability and Pharmacokinetics of CHF6523 in Healthy and in COPD Subjects Aug 1, 2019
- Personalized medicine for patients with COPD: where are we? Jul 9, 2019
