https://clinicaltrials.gov/ct2/show/NCT03679598?type=Intr&cond=COPD&phase=01234&lupd_s=12%2F13%2F2018&lupd_d=14&sort=nwst Alvelestat (MPH996) for the Treatment of ALpha-1 ANTitrypsin Deficiency Conditions : Alpha-1 Antitrypsin Deficiency (AATD); Pi*ZZ, Pi*SZ, or Pi*Null Phenotype; Emphysema or COPD Interventions : Drug: Alvelestat (MPH996); Other: Placebo Sponsors : University of Alabama at Birmingham; National Institutes of Health (NIH); Mereo BioPharma Not yet recruiting NCT03679598 Thu, 20 Sep 2018 12:00:00 EDT >>> updated dec 18, 2018